Darwin said, "If it could be demonstrated that any complex organ existed which could not possibly have been formed by numerous, successive, slight modifications, my theory would absolutely break down." Biochemist Michael Behe has demonstrated exactly that through his description of "irreducibly complex" molecular machines.
These complicated, microscopic contraptions, such as cilia and bacterial flagella, are extremely unlikely to have been built piece-by-piece through Darwinian processes, because they had to be fully present in order to function. Other examples include the incredible system of transporting proteins within cells and the intricate process of blood-clotting.
More than just a devastating challenge to Darwinism, these amazing biological systems -- which far exceed the capacity of human technology -- point toward a transcendent Creator. "My conclusion," said Behe, "can be summed up in a single word: design. I say that based on science. I believe that irreducibly complex systems are strong evidence of a purposeful, intentional design by an intelligent agent."
Behe's argument has proven impervious to challenges by skeptics. While obviously there will be future discoveries in biochemistry, Behe pointed out that they will not be able to negate the complexity that has already been discovered -- and which is best explained by a Creator.